Архів / Том LX 2020

Євгенія БІЛА, Дарина СОЛТИС, Микола ОБУШАК

Львівський національний університет імені Івана Франка, вул. Кирила і Мефодія, 6, 79005 Львів, Україна e-mail: vdutka@ukr.net

DOI: https://doi.org/10.37827/ntsh.chem.2020.60.031

ТРИКОМПОНЕНТНІ РЕАКЦІЇ НЕНАСИЧЕНИХ СПОЛУК З СОЛЯМИ АРЕНДІАЗОНІЮ І НЕЙТРАЛЬНИМИ НУКЛЕОФІЛАМИ. АРИЛСУЛЬФОНІЛЮВАННЯ

Підведено підсумки останніх досягнень щодо взаємодії солей арендіазонію з ненасиченими сполуками за наявності нейтральних нуклеофілів. Наведено нові приклади мультикомпонетних перетворень за участю таких нейтральних нуклеофілів як СО (арилкарбонілювання), NO (арилнітрозування), ацетонітрил (аміноарилювання), SO₂ (арилсульфонілювання) та інші. Ці реакції можуть бути застосовні до алкенів, алкінів, ароматичних сполук. Розглянуто реакції арилсульфонілювання алкенів за участю перехідних металів або в умовах metal-free-каталізу. Наведено приклади арилсульфонілювання зв’язку С=С з використанням сульфінових кислот, їхніх солей та гідразидів. Доступним методом одержання сульфонів є мультикомпонентна взаємодія солей арендіазонію, алкенів та SO₂. Використання функціоналізованих алкенів дає змогу отримувати функціоналізовані арилсульфони за одну стадію. Така функціоналізація розширює сферу використання арилсульфонів. Досягнуті успіхи у розробці ефективних стратегій одержання арилсульфонів відкривають нові можливості для подальших досліджень.

Ключові слова: арилювання, арилсульфонілювання, арендіазонієві солі, мультикомпонентні реакції, реакція Меєрвейна.

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Як цитувати:

Біла Є., Солтис Д., Обушак М. ТРИКОМПОНЕНТНІ РЕАКЦІЇ НЕНАСИЧЕНИХ СПОЛУК З СОЛЯМИ АРЕНДІАЗОНІЮ І НЕЙТРАЛЬНИМИ НУКЛЕОФІЛАМИ. АРИЛСУЛЬФОНІЛЮВАННЯ. Праці НТШ. Хім. наук. 2020 Т. LX. С. 31-54.

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